HAE symptoms
Symptoms can vary from person to person and attack to attack
Hereditary angioedema (HAE) can cause attacks of swelling in any part of the body, but characteristic locations include the skin (eg, face, hands, feet, genitals), stomach (abdomen), and throat. Before an attack, some patients experience early warning signs, also called prodromes, such as tingling, rash, fatigue, or nausea.
Skin, or cutaneous

- Swelling of the skin usually affects the hands, feet, face, or genitals
- Can be temporarily disfiguring and disabling and get in the way of everyday activities
- May be accompanied by redness, but the area usually doesn’t itch
Photos courtesy of US Hereditary Angioedema Association. www.haeimages.com.
Stomach, or abdomen

- Can cause mild to severe pain
- May be accompanied by vomiting and/or diarrhea
- Some patients experiencing untreated stomach (abdomen) attacks had to stay in bed between 24 and 50 hoursa
aIn a survey of 23 patients.
Photos courtesy of US Hereditary Angioedema Association. www.haeimages.com.
Throat, or larynx

- Causes swelling in the throat, also called a laryngeal attack
- Swelling in the throat can interfere with breathing, creating a potentially life-threatening situation
- May cause other symptoms, such as voice changes and difficulty swallowing
Photos courtesy of Bas M, et al. Allergy. 2006;61(12):1490-1492.