When to use FIRAZYR

With FIRAZYR, you can inject yourself as soon as you recognize the symptoms of an acute HAE attack after training under the guidance of a healthcare professional

FIRAZYR is used to treat acute attacks of hereditary angioedema (HAE) in adults 18 years of age and older. After starting treatment with FIRAZYR, knowing when — and why — to treat your HAE attacks can help you stay on track with the treatment plan you’ve discussed with your doctor. Here’s some helpful information to keep in mind.

Remember: HAE attacks can be debilitating and potentially life-threatening

  • Attacks can be unpredictable and can happen at any time without warning.
  • There is no way to tell how severe the next attack will be.


People with HAE, including those taking a preventive therapy, are strongly encouraged to have enough acute treatment for 2 attacks, or at least 2 doses, on hand to be prepared if an attack happens.


Laryngeal attacks can become life threatening. If you have an HAE attack of the throat (laryngeal attack), inject FIRAZYR and then go to the nearest hospital emergency room right away.

Guidelines recommend acute therapy be a part of every HAE treatment plan

  • Current guidelines recommend that people with HAE have an acute therapy as part of their treatment plan, so they are always prepared to treat if an unexpected attack occurs.
  • Guidelines recommend that you administer your acute treatment as early as possible in an attack and for all attacks, regardless of location, as soon as they are clearly recognized.


Because HAE attacks are unpredictable, always be ready to treat.

Rely on FIRAZYR when symptoms first appear

FIRAZYR is supplied in a 3-mL, prefilled, single-use syringe and is self-administered under the skin (subcutaneously) in the abdomen or stomach area, after training by a healthcare professional.

  • In the pivotal trial (Trial 1), FIRAZYR worked faster than placebo to resolve symptoms.
  • FIRAZYR was used to treat acute HAE attacks of the throat in 60 patients. Symptom reduction was similar to results seen for skin and abdominal attacks.


With FIRAZYR, you can inject yourself as soon as you recognize the symptoms of an acute HAE attack.

A real HAE patient testimonial: 'I really like the idea of being able to self-inject as soon as I realize I'm having an acute HAE attack.'

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