Treat HAE attacks both in and out of the home

FIRAZYR is a portable acute therapy option for adults 18 years of age and older that can go wherever you go, so you are always prepared to treat an attack if needed.

FIRAZYR is supplied as a 3-mL, prefilled, single-use syringe and is self-administered under the skin (subcutaneously) in the abdomen or stomach area.

  • You may self-administer FIRAZYR after training by a healthcare professional

If your symptoms are not resolved or if symptoms occur again after your first dose of FIRAZYR, additional doses can be administered at least 6 hours apart (no more than 3 doses in any 24-hour period).

Proven treatment that's ready if an unexpected attack occurs

FIRAZYR can be used to treat all types of acute HAE attacks, including skin (cutaneous), stomach (abdominal), and throat (laryngeal).

In the pivotal trial (Trial 1), the median time to 50% reduction in symptoms of skin or stomach attacks was 2.0 hours for those treated with FIRAZYR vs 19.8 hours for those given placebo

8 hours stopwatch representing FIRAZYR clinical trial symptom relief.

In Trial 1, the median time to almost complete symptom relief was 8.0 hours vs 36.0 hours for FIRAZYR and placebo, respectively

2-2.3 hours stopwatch representing the median time to 50% symptom reduction with FIRAZYR.

Across 3 controlled clinical trials, the median time to 50% reduction from baseline symptoms ranged from 2.0 to 2.3 hours with FIRAZYR

Pie chart showing how 9 out of 10 attacks were treated with a single dose of FIRAZYR.

In clinical trials, 9 of 10 attacks were treated with a single dose of FIRAZYR

In controlled studies:

  • FIRAZYR was used to treat acute HAE attacks of the throat in 60 people. Symptom reduction was similar to results seen for skin and abdominal attacks. It is important to know that laryngeal (throat) attacks can become life-threatening. If you have an HAE attack involving the throat, inject FIRAZYR as directed and then go to the nearest hospital emergency room right away.

Response to FIRAZYR for multiple attacks of acute HAE

Across controlled trials (FAST-1, -2 & -3), an analysis showed that the median time to 50% symptom reduction with FIRAZYR was consistent for up to 5 separate non-throat attacks.

The median time to 50% symptom reduction with FIRAZYR® was 2 hours for first and second attacks, 2.4 hours for third, 2 hours for fourth, and 1.5 hours for fifth.

Reach for FIRAZYR First

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