Meet Chaeli, a Shire Patient Ambassador

CHAELI: Hi, my name is Chaeli, and I am a senior in college. I experienced my first hereditary angioedema attack when I was 18 years old. Because it was in my face, I didn't think that — even though I had seen my mother experience facial swells over and over again, in my mind, it would never go away. In my mind, my face would be permanently swollen, and we struggled to get the swelling down, and that episode lasted for seven days.

That moment when I had my first attack, that moment took away my indestructible feeling. It does make me comfortable that I can have an open dialogue with my doctor because HAE; it still has mystery to it. My relationship with my healthcare team eventually led me to FIRAZYR. He told me that FIRAZYR was a new medication approved for adults 18 years old and older. He explained to me that, after being trained by a healthcare professional, I could inject FIRAZYR by myself when I feel an HAE attack coming on.

After talking to my doctor and my family, I decided to give FIRAZYR a chance. Being able to treat an acute attack on my own is a new feeling. I feel more prepared.

I encourage every patient living with hereditary angioedema to partner with their healthcare teams to find different treatment options that are available. It's important to have a support system in place when dealing with HAE, because HAE is unpredictable. You never know when it's gonna come for you. You never know when or where the attack will be, so it's important to have people there who know of your condition, who know what it is that you're going through, so that they can be there to encourage you.

NARRATOR: Indication: FIRAZYR® (icatibant injection) is a medicine used to treat acute attacks of hereditary angioedema (HAE) in adults 18 years of age and older.

Important Safety Information: Laryngeal attacks can become life threatening. If you have an HAE attack of the throat (laryngeal attack), inject FIRAZYR and then go to the nearest hospital emergency room right away.

The most common side effects of FIRAZYR include:

  • redness, bruising, swelling, warmth, burning, itching, irritation, hives, numbness, pressure, or pain at the injection site
  • fever
  • too much of an enzyme called transaminase in your blood
  • dizziness
  • nausea
  • headache
  • rash

The safety profile of FIRAZYR in patients who gave themselves the injection was similar to that in patients who had the injection given by a healthcare professional.

Tell your healthcare provider if you have any other medical conditions, if you are breastfeeding or plan to breastfeed, or if you are pregnant or planning to become pregnant. FIRAZYR has not been evaluated in pregnant or nursing women. You and your healthcare provider will decide if FIRAZYR is right for you.

If your symptoms continue or come back, you may repeat your FIRAZYR injection at least 6 hours apart. Do not use more than 3 doses of FIRAZYR in a 24-hour period.

Tiredness, drowsiness, and dizziness have been reported following the use of FIRAZYR. If this occurs, do not drive a car, use machinery, or do anything that needs you to be alert.

Tell your healthcare provider if you have any side effect that bothers you or that does not go away. For more information about FIRAZYR, ask your healthcare provider. For further information, please see the full Prescribing Information, including Patient Information. You can also call Shire at 1-866-888-0660.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit, or call 1-800-FDA-1088.