Causes of Hereditary Angioedema
HAE is often hereditary, but not always
As the name suggests, hereditary angioedema (HAE) is often passed through families. Literature suggests that about 75% of cases are inherited this way.
Still, about 25% of people with HAE have no family history at all. These cases result from a spontaneous change in the genetic code. Once this change happens, the altered gene and disease can be passed on to children.
HAE and your family
If you have HAE, you may find that the condition is common in your immediate and extended family. This could include your siblings, parents, aunts, uncles, cousins or grandparents.
If one parent has HAE, there is a 50% chance that his or her child will be affected.